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Transcriptome

 

Delloye-Bourgeois C, Bertin L, Thoinet K, Jarrosson L, Kindbeiter K, Buffet T, Tauszig-Delamasure S, Bozon M, Marabelle A, Combaret V, Bergeron C, Derrington E, Castellani V.Microenvironment-Driven Shift of Cohesion/Detachment Balance within Tumors Induces a Switch toward Metastasis in NeuroblastomaCancer Cell. 2017 Oct 9;32(4):427-443.e8. doi: 10.1016/j.ccell.2017.09.006. (RNA-Seqhttps://www.ncbi.nlm.nih.gov/pubmed/29017055

Chatagnon A, Veber P, Morin V, Bedo J, Triqueneaux G, Sémon M, Laudet V, d’Alché-Buc F, Benoit G
RAR/RXR binding dynamics distinguish pluripotency from differentiation associated cis-regulatory elements.
Nucleic Acids Res. 2015 May 26;43(10):4833-54. doi: 10.1093/nar/gkv370. Epub 2015 Apr 20. (RNA-seqhttp://www.ncbi.nlm.nih.gov/pubmed/25897113

Gras B, Jacqueroud L, Wierinckx A, Lamblot C, Fauvet F, Lachuer J, Puisieux A, Ansieau S
Snail Family Members Unequally Trigger EMT and Thereby Differ in Their Ability to Promote the Neoplastic Transformation of Mammary Epithelial Cells
PLoS One. 2014 Mar 17;9(3):e92254.  http://www.ncbi.nlm.nih.gov/pubmed/24638100

Caramel J, Papadogeorgakis E, Hill L, Browne GJ, Richard G, Wierinckx A, Saldanha G, Osborne J, Hutchinson P, Tse G, Lachuer J, Puisieux A, Pringle JH, Ansieau S, Tulchinsky E
A Switch in the Expression of Embryonic EMT-Inducers Drives the Development of Malignant Melanoma
Cancer Cell. 2013 Oct 14;24(4):466-80. http://www.ncbi.nlm.nih.gov/pubmed/24075834

Housset M, Samuel A, Ettaiche M, Bemelmans A, Béby F, Billon N, Lamonerie
Loss of otx2 in the adult retina disrupts retinal pigment epithelium function, causing photoreceptor degeneration
J. Neurosci. 2013 Jun 12;33(24):9890-904. doi: 10.1523/JNeurosc.1099-13.2013 . http://www.ncbi.nlm.nih.gov/pubmed/23761884

Dacheux E, Vincent A, Nazaret N, Combet C, Wierinckx A, Mazoyer S, Diaz JJ, Lachuer J, Venezia ND
BRCA1-Dependent Translational Regulation in Breast Cancer Cells
PLoS One. 2013 Jun 21;8(6):e67313. http://www.ncbi.nlm.nih.gov/pubmed/23805307

Altintas DM, Allioli N, Decaussin M, de Bernard S, Ruffion A, Samarut J, Vlaeminck-Guillem V
Differentially expressed androgen-regulated genes in androgen-sensitive tissues reveal potential biomarkers of early prostate cancer
PLoS One. 2013 Jun 28;8(6):e66278. http://www.ncbi.nlm.nih.gov/pubmed/23840433

Kratzer I, Liddelow SA, Saunders NR, Dziegielewska KM, Strazielle N, Ghersi-Egea JF
Developmental changes in the transcriptome of the rat choroid plexus in relation to neuroprotection
Fluids Barriers CNS. 2013 Aug 1;10(1):25. doi: 10.1186/2045-8118-10-25. http://www.ncbi.nlm.nih.gov/pubmed/23915922

Durand S, Nguyen XN, Turpin J, Cordeil S, Nazaret N, Croze S, Mahieux R, Lachuer J, Legras-Lachuer C, Cimarelli A
Tailored HIV-1 vectors for the genetic modification of primary human dendritic cells and monocytes
J Virol. 2013, Jan;87(1):234-42 http://www.ncbi.nlm.nih.gov/pubmed/23077304

Vasiljevic A, Champier J, Figarella-Branger D, Wierinckx A, Jouvet A, Fèvre-Montange M
Molecular characterization of central neurocytomas: potential markers for tumor typing and progression
Neuropathology. 2013 Apr;33(2):149-61 http://www.ncbi.nlm.nih.gov/pubmed/22816789

Magre S, Rebourcet D, Ishaq M, Wargnier R, Debard C, Meugnier E, Vidal H, Cohen-Tannoudji J, Le Magueresse-Battistoni B.
Gender differences in transcriptional signature of developing rat testes and ovaries following embryonic exposure to 2,3,7,8-TCDD. PLoS One. 2012;7(7):e40306. http://www.ncbi.nlm.nih.gov/pubmed/22808131

Mathieu C., Guillaume V.  Volchkova V., Pohl C., Jacquot F., Looi R. Y., Wong K.T., Legras-Lachuer C, Volchkov V., Lachuer J., and Horvat B.
Nonstructural Nipah Virus C Protein Regulates both the Early Host Proinflammatory Response and Viral Virulence
J.Virol. 2012 Oct;86(19):10766-75.

Loic Teulier, Cyril Dégletagne, Benjamin Rey, Jérémy Tornos, Céline Keime, Marc de Dinechin, Mireille Raccurt, Jean-Louis Rouanet, Damien Roussel and Claude Duchamp
Selective upregulation of lipid metabolism in skeletal muscle of foraging juvenile king penguins, an integrative study.
Proceedings of the Royal Society B : Biological Sciences, 2012 In press

Herbert M., Salomon A., Feige JJ. And Thomas M.
Acquisition Order of Ras and p53 Gene Alterations Defines Distinct Adrenocortical Tumor Phenotypes.
PLoS Genetics May;8(5):e1002700. Epub 2012 May 10.

Kratzer I, Vasiljevic A, Rey C, Fevre-Montange M, Saunders N, Strazielle N, Ghersi-Egea JF
Complexity and developmental changes in the expression pattern of claudins at the blood-CSF barrier
Histochem Cell Biol. 2012 Dec;138(6):861-79

Vendrell J., Thollet A., Nguyen NT., Ghayad SE., Vinot S., Bièche I., Grisard E., Josserand V., Coll JL., Roux P., Corbo L., Treilleux I., Rimokh R., and PA. Cohen
High ZNF217 mRNA level is a novel marker for poor prognosis in breast cancer and ZNF217 overexpression is associated with migration, invasion and EMT
Cancer Research. 2012 May 25.

Anne-Pierre Morel, George W. Hinkal, Clémence Thomas, Frédérique Fauvet, Stéphanie Courtois-Cox, Anne Wierinckx, Mojgan Devouassous-Shisheboran, Agnes Tissier, Baptiste Gras, Julie Pourchet, Isabelle Puisieux, Gareth Browne, Douglas B. Spicer, Joel Lachuer, Stéphane Ansieau, and Alain Puisieux
EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice.
PLoS Genetics 2012 May;8(5):e1002723.

Hiriart E, Vavasseur A, Touat-Todeschini L, Yamashita A, Gilquin B, Lambert E, Perot J, Shichino Y, Nazaret N, Boyault C, Lachuer J, Perazza D, Yamamoto M, Verdel A
Mmi1 RNA surveillance machinery directs RNAi complex RITS to specific meiotic genes in fission yeast
EMBO J. 2012 Apr 20;31(10):2296-308

Champier J. , Claustrat F., Nazaret N., Fèvre Montange M. and B. Claustratb
Folate depletion changes gene expression of fatty acid metabolism, DNA synthesis, and circadian cycle in male mice
Nutrition Res. 2012 32 124–132

Mathieu C., Vanessa G., Amélie S., Chai Ong K., K. Wong T., Legras-Lachuer C. and Horvat B.
Lethal Nipah virus infection induces rapid overexpression of CxCl10
Plos One 2012;7(2):e32157. Epub 2012 Feb 29.

Vasiljevic A, Champier J, Figarella-Branger D, Wierinckx A, Jouvet A, Fèvre-Montange M.
Molecular characterization of central neurocytomas: Potential markers for tumor typing and progression
Neuropathology. 2012 Jul 23. doi: 10.1111/j.1440-1789.2012.01338

Szathmari A, Champier J, Ghersi-Egea JF, Jouvet A, Watrin C, Wierinckx A, Fèvre Montange M.
Molecular characterization of circumventricular organs and third ventricle ependyma in the rat: potential markers for periventricular tumors
Neuropathology. 2012 Apr 27. doi: 10.1111/j.1440-1789.2012.01321

Morgan Thenoz, Céline Vernin, Christiane Pinatel, Nicolas Nazaret, Joel Lachuer, Didier Auboeuf, Eric Wattel, Franck Mortreux
1 HTLV-1 modulates alternative splicing in CD4+ T cells in vivo 8 (Suppl 1):A168

Mathieu C. Legras-Lachuer C., Horvat B.
Transcriptome signature of Nipah virus infected endothelial cells
Vasculitis, 2011 In : Advances in Etiology, Pathogenesis and Pathology of Vasculitis, Edited by L.M. Amezcua-Guerra, InTech Open access publisher, p.3-21, ISBN 978-953-307-651-5,

Sabbah, C. Prunier, N. Ferrand, V. Megalophounos, K. Lambein, O. De Wever, N. Nazaret, J. Lachuer, S. Dumont and G. Redeuilh
CCN5, a novel transcriptional repressor: its roles in transforming growth factor-b signalling pathway
Mol cell Biol. 2011 Apr;31(7):1459-69.

Boutahar N, Wierinckx A, Camdessanche JP, Antoine JC, Reynaud E, Lassabliere F, Lachuer J, Borg J.
Differential effect of oxidative or excitotoxic stress on the transcriptional profile of amyotrophic lateral sclerosis-linked mutant SOD1 cultured neurons
J Neurosci Res. 2011 Sep;89(9):1439-50. doi: 10.1002/jnr.22672. Epub 2011 Jun 6.

Hesling C, Fattet L, Teyre G, Jury D, Gonzalo P, Lopez J, Vanbelle C, Morel AP, Gillet G, Mikaelian I, Rimokh R
Antagonistic regulation of EMT by TIF1γ and Smad4 in mammary epithelial cells
EMBO Rep. 2011 Jul 1;12(7):665-72

Jordheim LP, Plesa A, Dreano M, Cros-Perrial E, Keime C, Herveau S, Demangel D, Vendrell JA, Dumontet C
Sensitivity and gene expression profile of fresh human acute myeloid leukemia cells exposed ex vivo to AS602868
Cancer Chemother Pharmacol. 2011 Jul;68(1):97-105

Wierinckx A, Raverot G, Nazaret N, Jouanneau E, Auger C, Lachuer J, Trouillas J
Proliferation markers of human pituitary tumors: Contribution of a genome-wide transcriptome approach
Mol Cell Endocrinol. 2010 326 (1-2) : 30-39.

Raverot G, Wierinckx A, Dantony E, Auger C, Chapas G, Villeneuve L, Brue T, Figarella-Branger D, Roy P, Jouanneau E, Jan M, Lachuer J, Trouillas J
HYPOPRONOS. Prognostic factors in prolactin pituitary tumors: clinical, histological, and molecular data from a series of 94 patients with a long postoperative follow-up
J Clin Endocrinol Metab. 2010 Apr;95(4):1708-16

Zane L, Sibon D, Legras-Lachuer C, Lachuer J, Wierinckx A, Mehlen P, Delfau-Larue MH, Gessain A, Gout O, Pinatel C, Lançon A, Mortreux F, Wattel E
Clonal expansion of HTLV-1 positive CD8(+) cells relies on cIAP-2 but not on c-FLIP expression
Virology. 2010 407 (2) 341-351

Caillier M., Thénot S., Tribollet V., Birot A.M. Samarut J. and A. Mey
Role of the epigenetic regulator HP1g in the control of embryonic stem cell properties
PLoS One, 2010. Nov 15(5):e15507.

Berthier-Vergnes O, Kharbili ME, de la Fouchardière A, Pointecouteau T, Verrando P, Wierinckx A, Lachuer J, Le Naour F, Lamartine J
Gene expression profiles of human melanoma cells with different invasive potential reveal TSPAN8 as a novel mediator of invasion
Br J Cancer. 2010 Nov 16 104(1):155-65.

Popovici J, Comte G, Bagnarol E, Alloisio N, Fournier P, Bellvert F, Bertrand C, Fernandez MP
Differential effects of rare specific flavonoids on compatible and incompatible strains in the Myrica gale-Frankia actinorhizal symbiosis.
Appl Environ Microbiol. 2010 Apr;76(8):2451-60. Epub 2010 Feb 26.

Alloisio N, Queiroux C, Fournier P, Pujic P, Normand P, Vallenet D, Medigue C, Yamaura M, Kakoi K, Kucho K-I
The Frankia alni symbiotic transcriptome
Molecular Plant-Microbe Interactions 2010: 23, 593-607

Degletagne C, Keime C, Rey B, de Dinechin M, Forcheron F, Chuchana P, Jouventin P, Gautier C, Duchamp C
Transcriptome analysis in non-model species: a new method for the analysis of heterologous hybridization on microarrays
BMC Genomics. 2010 May 31;11:344.

Laurence Josset, Julien Textoris, Béatrice Loriod, Olivier Ferraris, Vincent Moules, Bruno Lina, Catherine N’Guyen, Jean-Jacques Diaz, Manuel Rosa-Calatrava
Gene Expression Signature-Based Screening Identifies New Broadly Effective Influenza A Antivirals
PLoS One. 2010 Oct 4;5(10).

Béby F, Housset M, Fossat N, Le Greneur C, Flamant F, Godement P,  Lamonerie T
Otx2 Gene Deletion in Adult Mouse Retina Induces Rapid  RPE Dystrophy and Slow Photoreceptor Degeneration
PLoS ONE 2010. 5 (7): e11673.

Michallet, Marie-Cecile, Leverrier, Yann, Baguet, Joel, Chambion, Solene, Marvel, Jacqueline
Activation of inflammation and innate immune signaling pathways by transcriptionnal stress
Bulletin du cancer. Mar 2010  Volume: 97   Special Issue: SI Pages: S31-S31.

Gallois A., Lachuer J., Yvert G., Wierinckx A., Brunet F., Rabourdin-Combe C., Delprat C.L, Jurdic P and Mazzorana M.
Genome-wide expression analysis establish dendritic cells as a new osteoclast precursor able to generate bone resorbing cells more efficiently than monocytes
Journal of Bone and Mineral Research, 2010 Mar;25(3):661-72

Ginguené C, Champier J, Maallem S, Strazielle S,, Jouvet A, Fèvre-Montange, M, Ghersi-Egea, JF
P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) localize in the microvessels forming the blood-tumor barrier in ependymomas
Brain Pathol, 2010, 5:926-35.

Deniaud E.,Baguet J., Chalard R, Blanquier B., Brinza L., Laugraud A.,Ah-Soon C, Castellazzi M., Lachuer J.,Gautier C, Marvel J., Leverrier Y.
Transcriptional and cellular perturbations associated with the binding of deregulated transcription factor Sp1 to DNA
Plos One, 2009:Sep 15;4(9).

Bidon C., J. Lachuer, J. Molgó, A. Wierinckx, Y. Christen, J. Mallet, H. Koenig, R. Meloni and N. Faucon Biguet
Extracts of Gingko Biloba (EGB 761) reactivate a juvenile profil in skeletal muscle of sarcopenic rats by transcriptional reprogramming
Plos one: 2009. 24;4(11) e7998.

Ghayad SE, Vendrell JA, Bieche I, Spyratos F, Dumontet C, Treilleux I, Lidereau R, Cohen PA
Identification of TACC1, NOV, and PTTG1 as new candidate genes associated with endocrine therapy resistance in breast cancer
J. Mol.  Endocrinol. 2009 42, 87-103.

Maallem S., Wierinckx A., Lachuer J., Kwon MH and Tappaz ML
Gene expression profiling in brain following acute systemic hypertonicity : novel genes possibly involved in osmoadaptation
J. Neurochem 2008, 105 (4) : 1198-1211

Djebali S., Tebib J., Brytting M., Egeler RM., Rabourdin-Combe C., Henter JL., Arico M., Delprat C.
Langherans cell histiocytosis reveals a new IL-17A-dependant pathway of dendritic cell fusion
Nat. Med. 2008 14 (1) 81-87

Coury F., Annels N., Rivollier A., Olsson S., SAntoro A., Speziani C., Azocar O., Flacher M.,Ansieau S, Bastid J, Doreau A, Morel AP, Bouchet BP, Thomas C, Fauvet F, Puisieux I, Doglioni C, Piccinin S, Maestro R, Voeltzel T, Selmi A, Valsesia-Wittmann S, Caron de Fromentel C, Puisieux A
Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence
Cancer Cell 2008 14 (1) : 79-89

Mazaud Guittot, Adelie Verot, F. Odet, MA Chauvin and B. le Magueresse-Battistoni
A comprehensive survey of the laminins and collagens type IVexpressed in mouse Leydig cells and their regulation by LH/hCG. A comprehensive survey of the laminins and collagens type IV expressed in mouse Leydig cells and their regulation by LH/hCG
Reproduction. 2008 . pages

Vendrell JA, Robertson KE, Ravel P, Bray SE, Bajard A, Purdie CA, Nguyen C, Hadad SM, Bieche I, Chabaud S, Bachelot T, Thompson AM, Cohen PA
A candidate molecular signature associated with tamoxifen failure in primary breast cancer.
Breast Cancer Res. (2008) 10, R88, 1-17. Comments in Editorial: “Approaches towards expression profiling the response to treatment » by A.H Sims and JMS Bartlett, Breast Cancer Res. 2008 10, 115-16.135(4):479-88.

Leverrier, Yann, Deniaud, E., Baguet, Joel, Chalard, R, Ah-Soon, C., Laugraud, A., Gautier, C., Marvel, J., Leverrier, Y.
Cell cycle arrest, apoptosis induction and transcriptional profiling following overexpression of transcription factor Sp1
Bulletin du cancer.  Mar 2008 Volume: 95   Special Issue: SI   Pages: S90-S91 Published.

Ghayad S., Bieche I., Vendrell J., Keime C., Lidereau R., Dumontet C. and Cohen P.
mTOR inhibition reverses acquired endocrine therapy resistance of breast cancer cells at the cell proliferation and gene expression levels
Cancer Science 2008 vol 99 n°10 : 1992-2003

Ducray F., Honnorat J., Lachuer J.
DNA microarray technology: principles and applications to the study of neurological disorders
Rev Neurol , 2007, 163 ; 409-420

Wierinckx A, Auger C, Devauchelle P, Reynaud A , Chevallier P, Fèvre-Montange M, Rey C, Figarella-Branger D, Belin MF,Trouillas J and Lachuer J
A Diagnostic Marker Set for Invasion and Proliferation
Endocrine Related Cancer. 2007, 14 (3) 887-900. * equal contribution.

De Martino I, Fedele M, Palmieri D, Visone R, Cappabianca P, Wierinckx A, Trouillas J, Fusco A
B-RAF mutations are a rare event in pituitary adenomas
J Endocrinol Invest. 2007 Jan;30(1):RC1-3

Fèvre-Montange M, Champier J, Szathmari A, Wierinckx A, Mottolese C, Guyotat J, Figarella-Branger D, Jouvet A, Lachuer J
Microarray analysis reveals differential gene expression patterns in tumors of the pineal region
J Neuropathol Exp Neurol, 2006; 65:675-84.

Fontanière, J. Tost, A. Wierinckx, J. Lachuer, F. Busato, I.
Gut, Z-Q Wang and C-X Zang Gene expression profiling in insulinoma of men1 beta-cell mutant mice reveals early genetic and epigenetic events involved in pancreatic beta-cell tumorigenesis.
Endocrine Related Cancer, 2006 Dec;13(4):1223-36

Tozlu S, Girault I, Vendrell J, Vacher S, Cohen P, Lidereau R, Bièche I
Identification of novel genes that co-cluster with estrogen receptor alpha in breast tumor biopsies using a large scale real-time RT-PCR approach
Endocrine-related Cancer 2006 13, 1109–20.

Lachuer J., Ouyang L., Legras C., Del Rio J and Barlow C
Gene expression profiling reveals an inflammatory process in the anx/anx mutant mice
Brain Res Mol Brain Res., 2005 Oct 3;139(2):372-6.

Lukaszewicz A, Savatier P, Cortay V, Giroud P, Huissoud C, Berland M, Kennedy H, Dehay C
G1 phase regulation, area-specific cell cycle control, and cytoarchitectonics in the primate cortex
Neuron, 2005, Aug 4;47(3):353-64

Vendrell JA., Bieche I., Desmetz C., Badia E., Tozlu S., NGuyen C., Nicolas JC., Lidereau R., Cohen P.
Molecular changes associated with the agonist activity of hydroxy-tamoxifen and the hyper-response to estradiol in hydroxy-tamoxifen-resistant breast cancer cell lines.
Endocrine-related Cancer, 2005, 12:1-18.

JA Vendrell, F Magnino, E Danis, MJ Duchesne, S Pinloche, M Pons, D Birnbaum, C Nguyen, C Theillet and PA Cohen
Estrogen regulation in human breast cancer cells of new downstream gene targets involved in estrogen metabolism, cell proliferation and cell transformation
J. Mol. Endocrinol 2004, 32, 397-414

Caceres M., Lachuer J., Zappala MA, Redmond JC., Kudo L., Gechwind DH., Lockhart DJ., Preuss TM and Barlow C
Elevated gene expression levels distinguish human from non-human primate brains
Proc Natl Acad Sci USA, 2003. 28;100(22):13030-5