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Méthylome

Burel-Vandenbos F, Pierron G, Thomas C, Reynaud S, Gregoire V, Duhil De Benaze G, Croze S, Chivoret N, Honavar M, Figarella-Branger D, Maurage CA, Pedeutour F, Hasselblatt M, Godfraind C. A polyphenotypic malignant paediatric brain tumour presenting a MN1-PATZ1 fusion, no epigenetic similarities with CNS High-Grade Neuroepithelial Tumour with MN1 Alteration (CNS HGNET-MN1) and related to PATZ1-fused sarcomas. Neuropathol Appl Neurobiol. 2020 May 12. doi: 10.1111/nan.12626. [Epub ahead of print] PMID: 32397004 https://www.ncbi.nlm.nih.gov/pubmed/32397004 (DNA methylation, Beadarray 850K, FFPE, cancer)

Bouzid A, Smeti I, Dhouib L, Roche M, Achour I, Khalfallah A, Gibriel AA, Charfeddine I, Ayadi H, Lachuer J, Ghorbel A, Petit C, Masmoudi S. Down-expression of P2RX2, KCNQ5, ERBB3 and SOCS3 through DNA Hypermethylation in Elderly Women with Presbycusis.  Biomarkers. 2018 Jan 11:1-24. (methylation by RRBS). https://www.ncbi.nlm.nih.gov/pubmed/29325454

Doñate Puertas R, Meugnier E, Romestaing C, Rey C, Morel E, Lachuer J, Gadot N, Scridon A, Julien C, Tronc F, Chapuis B, Valla C, Janin A, Pirola L, Méjat A, Rome S, Chevalier P. Atrial fibrillation is associated with hypermethylation in human left atrium, and treatment with decitabine reduces atrial tachyarrhythmias in spontaneously hypertensive rats. Transl Res. 2017 Jun;184:57-67 (PCR, Sanger and methylation) https://www.ncbi.nlm.nih.gov/pubmed/28427903

Devailly G, Grandin M, Perriaud L, Mathot P, Delcros JG, Bidet Y, Morel AP, Bignon JY, Puisieux A, Mehlen P, Dante R.
Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells.
Nucleic Acids Res. 2015 Jul 13;43(12):5838-54. doi: 10.1093/nar/gkv508. Epub 2015 May 24. http://www.ncbi.nlm.nih.gov/pubmed/26007656

Chatagnon A, Perriaud L, Nazaret N, Croze S, Benhattar J, Lachuer J, Dante R.
Preferential binding of the methyl-CpG binding domain protein 2 at methylated transcriptional start site regions.
Epigenetics. 2011 Nov;6(11):1295-307. doi: 10.4161/epi.6.11.17875. Epub 2011 Nov 1.

Chatagnon A, Bougel S, Perriaud L, Lachuer J, Benhattar J, Dante R.
Specific association between the Methyl-CpG binding domain protein 2 and the hypermethylated region of the human telomerase reverse transcriptase promoter in cancer cells.
Carcinogenesi. 2009 Jan;30(1):28-34